神经递质与受体-神经科学百科全书

节选

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《神经科学百科全书4:神经递质与受体(影印版)》内容简介：《神经科学百科全书》原书篇幅巨大，为所有神经科学百科全书之首。由来自世界各地的2400多位专家撰稿人合力打造，覆盖了神经科学全部主要领域。书中每个词条在收入书中之前均经过顾问委员会的同行评议，词条中均含有词汇表、引言、参考文献和丰富的交叉参考内容。

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相关资料

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插图：For many years, the understanding of neurotransmis-sion has been dominated by the concept that oneneuron releases only a single transmitter, known as’Dale’s Principle.’ This idea arose from a widelyadopted misinterpretation of Dale’s suggestion in1935 that the same neurotransmitter was stored inand released from all terminals of a single neuron, asuggestion which did not specifically preclude thepossibility that more than one transmitter may beassociated with the same neuron. Several lines of evi-dence emerged which were inconsistent with the sin-gle transmitter concept, and it is now known thatindividual neurons contain and can release a largenumber and variety of substances which are capableof influencing target cells. This phenomenon of’cotransmission’ is widespread, involving virtuallyall known transmitter systems. Early hints of cotransmission came in the 1950swith evidence for the involvement of both noradren-aline （NA） and acetylcholine （ACh） in sympathetictransmission. Koelle identified acetylcholinesterase insome adrenergic neurons in 1955, while Burn andRand introduced the concept of a ‘cholinergic’ linkin adrenergic transmission in 1959. Another line ofevidence provided by Hillarp concerned the coexis-tence of adenosine 5′-triphosphate （ATP） with cate-cholamines, first in adrenal chromaffin Cells and laterin sympathetic nerves. Inconsistencies in the singletransmitter hypothesis provided by these and otherstudies from the early literature were rationalized inan article by Burnstock in 1976 with the provocativetitle,”Do some nerve cells release more than one trans-mitter？” Today it is widely accepted that cotransmis-sion is an integral feature of neurotransmission. A role for ATP as a cotransmitter in sympathetic,parasympathetic, sensory-motor, and enteric nonadre-nergic, noncholinergic （NANC） inhibitory nerves wassupported by research from Burnstock and colleagues,while H6kfelt and colleagues focused on the co-localization, vesicular storage, and release of peptidesfrom both peripheral and central nerves.

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本书特色

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《神经科学百科全书4:神经递质与受体(影印版)》：主编为著名神经科学家、美国神经科学学会前主席Larry R．Squire。内容平易，本科生即可读懂。深度和广度独一无二，足可满足专家学者的需要。导读版精选原书中的部分主题，按内容重新编排，更适合国内读者购买和阅读。

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目录

神经递质与受体Astrocyte: Neurotransmitter and Hormone ReceptorsCotransmissionNeuropeptides and CoexistenceNeurotransmitter and Hormone Receptors on Oligodendrocytes and Schwann CellsNeurotransmitters and Growth Factors: OverviewNitric Oxide氨基酸与嘌呤AdenosineAdenosine Triphosphate (ATP)Adenosine Triphosphate (ATP) as a NeurotransmitterAMPA Receptor Cell Biology/TraffickingAMPA Receptors: DiseaseAMPA Receptors: Molecular Biology and PharmacologyCalcium Waves: Purinergic RegulationD-Serine: From Its Synthesis in Giial Cell to Its Action on Synaptic Transmission and PlasticityGABA Synthesis and MetabolismGABAA Receptor Synaptic FunctionsGABAA Receptors and DiseaseGABAA Receptors: Developmental RolesGABAA Receptors: Molecular Biology, Cell Biology, and PharmacologyGABAB Receptor FunctionGABAn Receptors: Molecular Biology and PharmacologyGamma-Aminobutyric Acid (GABA)Glial Glutamate Transporters: ElectrophysiologyGlutamateGlutamate Receptor Clusters: Narp, EphB2 Receptor, StargazinGlutamate Receptor Organization: Ultrastructural InsightsGlutamate Regulation of Dendritic Spine Form and FunctionGlutamatergic and Gabaergic SystemsGlycine Receptors: Molecular and Cell BiologyHerbal Products and GABA Receptors Kainate Receptor Functions Kainate Receptors: Molecular and Cell BiologyLong-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent FormsLong-Term Potentiation (LTP): NMDA Receptor RoleLong-Term Potentiation and Long-Term Depression in Experience-Dependent PlasticityMetabotropic Glutamate Receptors (mGluRs): FunctionsMetabotropic Glutamate Receptors (mGluRs): Molecular Biology, Pharmacology and Cell BiologyNMDA Receptor Function and Physiological ModulationNMDA Receptors and DevelopmentNMDA Receptors and DiseaseNMDA Receptors, Cell Biology and TraffickingP2X ReceptorsPharmacology of Sleep: AdenosinePostsynaptic Density/Architecture at Excitatory SynapsesPurinergic ReceptorsPurines and Purinoceptors: Molecular Biology OverviewTransporter Proteins in Neurons and Glia胺与乙酰胆碱Acetylchollne Neurotransmission in CNSAcetylcholinesteraseAcetylchollnesterase Inhibitors and Alzheimer’s DiseaseAdenosine Receptor Mediated FunctionsAdrenergic ReceptorsAmphetaminesAttention Deficit Hyperactivity Disorder (ADHD): Methylphenidate (Ritalin) and DopamineAversive Emotions: Genetic Mechanisms of SerotoninBrain Adrenergic NeuronsCells: 5-Hydroxytryptamine ReceptorsCholinergic Neurotransmission in the Autonomic and Somatic Motor Nervous System.Chollnergic Pathways in CNSCholinergic SystemDopamineDopamine-CNS Pathways and NeurophysiologyDopamlne Control of ArousalDopanune in Perspective Dopannne Neurons: Reward and UncertaintyDopannne Receptors and Antipsychotic Drugs in Health and DiseaseDopannne: Cellular ActionsDopaminergic Agonists and L-DOPAHistamine Receptors and their Ligands: Mechanisms and Applications3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)Monoamine Transporters: Focus on the Regulation of Serotonin Transporter by CytokinesMonoaminesMonoamines: Human Brain ImagingMonoamines: Release StudiesMuscarinic Receptors: Autonomic NeuronsNeurolepticsNeutrotransmission and Neuromodulation: AcetylcholineNicotineNicotinic Aeetylcholine ReceptorsNicotinic Receptors: Autonomic NeuronsNoradrcnaline Norepinephrine: Adrenergic ReceptorsNorcpinephrine: CNS Pathways and NeurophysiologyOctopamine and Other Monoamines in InvertebratesSerotonin (5-Hydroxytryptamine; 5-HT): Neurotransmissionand NeuromodulationSerotonin (5-Hydroxytryptamine; 5-HT): CNS Pathways and NeurophysiologySerotonin (5-Hydroxytryptamine; 5-HT): ReceptorsSerotonin and the Regulation of Mammalian Circadian RhythmsSerotonin-Related Psychedelic Drugs Sleep-Wake State Regulation by AcetylcholineSympathomimetic Drugs and Adrenergic Receptor AntagonistsTrace Monoamines and Receptors in Mammalian CNS原书词条中英对照表

封面

书名:神经递质与受体-神经科学百科全书

作者:斯奎尔(Larry R.Squire)

页数:未知

定价:¥168.0

出版社:科学出版社

出版日期:2010-08-01

ISBN:9787030280862

PDF电子书大小:157MB 高清扫描完整版