转化生物信息学及其应用:英文版_PDF下载[46MB-百度云]魏冬青等著

内容简介

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本书整合了基础生物信息学、临床信息学、统计遗传学的综合性研究领域, 通过分析大量的临床数据, 理解疾病发生发展的分子基础, 并形成系统性的临床应用知识体系。

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Part I Computer-Aided Drug Discovery 1 Drug Discovery Geetha Ramakrishnan 2 Translational Bioinformatics and Drug Discovery Pramodkumar Pyarelal Gupta 3 Translational Research in Drug Discovery and Development Neha Arora, Pawan Kumar Maurya, and Puneet Kacker 4 Exploring the Potential of Herbal Ligands Toward Multidrug-Resistant Bacterial Pathogens by Computational Drug Discovery Sinosh SkariyachanPart II Protein-Ligand Interactions and Drug Development 5 The Progress of New Targets of Anti-HIV and Its Inhibitors Ke Z. Wu and Ai X. Li 6 Recent Studies on Mechanisms of New Drug Candidates for Alzheimer’s Disease Interacting with Amyloid-β Protofibrils Using Molecular Dynamics Simulations Huai-Meng Fan, Qin Xu, and Dong-Qing Wei 7 Homology Modelling, Structure-Based Pharmacophore Modelling, High-Throughput Virtual Screening and Docking Studies of L-Type Calcium Channel for Cadmium Toxicity Madhu Sudhana Saddala and A. Usha Rani 8 Natural Compounds Are Smart Players in Context to Anticancer Potential of Receptor Tyrosine Kinases: An In Silico and In Vitro Advancement Pushpendra Singh, Shashank Kumar, and Felix BastPart III Omics for Precision Medicine 9 Genome-Wide Association Studies: A Comprehensive Tool to Explore Comparative Genomic Variations and Interactions Aruni Wilson 10 A Survey of Bioinformatics-Based Tools in RNA-Sequencing (RNA-Seq) Data Analysis Pall**i Gaur and Anoop Chaturvedi 11 Epigeics and Its Role in Human Cancer Utkarsh Raj and Pritish Kumar Varadwaj 12 Methods for Microhiome Analysis Kalibulla Syed Ibrahim and Nachimuthu Senthil Kumar 13 Pharmacogenomics: Clinical Perspective, Strategies,and Challenges Dev Bukhsh SinghPart IV Biostatistics, Bioinformatics, and System Biology Approaches to Complex Diseases 14 Computational Network Approaches and Their Applications for Complex Diseases Ankita Shukla and Tiratha Raj Singh 15 Bioinformatics Applications in Clinical Microbiology Chao Zhang, Shunfu Xu, and Dong XuPart V Bioimaging and Other Applications of Informatics Techniques in Translational Medicine 16 Artificial Intelligence and Automatic Image Interpretation in Modern Medicine Costin Teodor Streba, Mihaela Ionescu, Cristin Constantin Vere, and Ion Rogoveanu 17 Computation in Medicine: Medical Image Analysis and Visualization Adekunle Micheal AdeshinaIndex